Open-source, vendor-agnostic deep learning pipeline that retrospectively measures left ventricular global longitudinal strain (GLS) from routine apical-4-chamber echocardiography B-mode video, without requiring speckle-tracking software or manual tracing. The pipeline reuses EchoNet-Dynamic's LV semantic-segmentation network to trace the LV endocardial border frame-by-frame, then measures the frame-to-frame change in traced myocardial length across the cardiac cycle to derive GLS. In external validation against a large 3D-echocardiography-derived GLS dataset and a prospective two-sonographer, two-vendor repeated-measures study, the automated strain measurement showed lower inter- and intra-measurement variability than human readers and moderate agreement with reference speckle-tracking strain (ICC 0.58), while being robust to image-quality differences and vendor.

Pediatric-specific extension of EchoNet-Dynamic: a video-based deep learning model that segments the left ventricle and estimates ejection fraction (EF) from apical-4-chamber (A4C) and parasternal short-axis (PSAX) pediatric echocardiogram clips. Because adult-trained echo models generalize poorly to children (who vary widely in heart size, rate, and image quality), EchoNet-Peds was trained from scratch on a dedicated pediatric video dataset. It segments the LV with a Dice similarity coefficient of 0.89 in both views, estimates EF with a mean absolute error of 3.66%, and identifies pediatric systolic dysfunction with an AUC of 0.95, significantly outperforming an adult-trained model applied to the same pediatric data.

Adapts the Segment Anything Model (SAM) to echocardiography video segmentation by giving it a space-time memory that carries both spatial and temporal cues, so that only the first frame of a video needs an external point prompt and every subsequent frame is segmented from a propagated memory prompt instead. A memory reinforcement mechanism uses each frame's predicted mask to suppress speckle-noise features before they are written back into memory, addressing a key failure mode of naively adapting video object segmentation (e.g. XMem) to noisy ultrasound. Built on SAMUS (an ultrasound-adapted SAM) with a frozen SAM backbone and only the image-encoder adapter layers trained. On the semi-supervised CAMUS and EchoNet-Dynamic benchmarks (only end-diastole/end-systole frames labeled), MemSAM reaches 93.3% and 92.8% mean Dice respectively, outperforming UNet, SwinUNet, H2Former, and prior medical-SAM adaptations (MedSAM, MSA, SAMed, SonoSAM, SAMUS) with far fewer prompts, and derives LVEF (via Simpson's biplane method of disks) with a Pearson correlation of 78.9% against ground truth on CAMUS. Training/inference code is public (MIT license); only the starting SAM ViT-B checkpoint is linked for download, not a separately released fine-tuned MemSAM checkpoint.

Vision-language foundation model fine-tuned from CLIP on more than one million private echocardiogram video-report pairs, enabling zero-shot cardiac function assessment, device identification, and image/text retrieval without task-specific training. Combines a ConvNeXt-Base video encoder with a GPT-2-style text encoder under contrastive pretraining. Training data is private, but model weights and code are public. Developed by Cedars-Sinai's Ouyang lab.

End-to-end pipeline for apical-4-chamber echocardiogram videos that segments the left ventricle, estimates ejection fraction on a beat-to-beat basis, and classifies cardiomyopathy with reduced ejection fraction. Combines a DeepLabV3-ResNet50 segmentation model with a 3D CNN (R2+1D/R3D/MC3) initialized on the Kinetics-400 video dataset. Trained on the public EchoNet-Dynamic dataset released alongside it, and one of the most widely reused open echocardiography models since its 2020 Nature publication. Developed by Stanford University.

View-agnostic, multi-task model that performs 39 different echocardiographic reporting tasks - covering chamber size and function, valve disease, and more - from any combination of views, aggregating clip-level predictions up to the study level. Combines a ConvNeXt-Tiny frame encoder with a temporal Transformer and separate output heads per task. Trained on private Yale-New Haven Health System echo videos and published in JAMA in 2025 by Yale's CarDS Lab.