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Open, transparent deep-learning method for measuring left ventricular global longitudinal strain (GLS) from routine 2D echocardiography, built as an alternative to proprietary vendor strain software. Unity-GLS is a multi-image neural network (based on the HigherHRNet-W32 pose-estimation architecture) that identifies the mitral annulus, LV apex, and endocardial curve from a target frame plus six neighbouring frames, across apical 4-, 3-, and 2-chamber views. Validated against multi-expert (11-reader) consensus tracings from 100 echocardiograms in a UK-wide collaborative, Unity-GLS agreed with expert consensus as strongly as individual human experts and two proprietary vendor packages (correlation with consensus: 0.91 vs. 0.73-0.85 for other methods).
Model ID: 0132