ECG-guided photoplethysmography (PPG) foundation model pretrained on over 100,000 hours of synchronized PPG-ECG recordings from 58,796 subjects across five clinical and wearable sources, using a CLIP-style contrastive alignment framework so the PPG encoder inherits physiologically grounded structure from paired ECG. Achieves state-of-the-art performance on 13 of 15 conventional physiological-analysis tasks across eight datasets, and shows meaningful discriminative capability (AUC >= 0.70) for 307 ICD-10-coded phenotypes across 16 phecode chapters, including many non-cardiovascular conditions.

Supervised EfficientNetV2-based 12-lead ECG model trained on over 1 million ECGs from the Montreal Heart Institute to predict 77 cardiac conditions derived from American Heart Association recommendations, plus fine-tuned digital-biomarker heads for reduced LVEF, 5-year atrial-fibrillation risk, and long-QT-syndrome (LQTS) detection/genotyping. Validated on 881,403 ECGs across 11 geographically diverse cohorts (4 public, 7 private health systems), achieving AUROCs above 0.98 for the 77-condition interpretation task while being 60x smaller and 29x faster at inference than its self-supervised DeepECG-SSL counterpart, with up to 9.7x lower CO2 emissions on equivalent tasks.

Self-supervised EfficientNetV2-based 12-lead ECG foundation model pretrained via contrastive learning and masked-lead modeling on 1.9 million ECGs (Montreal Heart Institute plus CODE-15% and MIMIC-IV), then fine-tuned for the same 77-condition ECG interpretation task and digital-biomarker extraction as DeepECG-SL. Outperforms the supervised counterpart on label-scarce digital-biomarker tasks, with the largest gains on LQTS genotype classification (AUROC 0.931 vs. 0.850, n=127 ECGs) and 5-year atrial-fibrillation risk (AUROC 0.742 vs. 0.734, n=132,050 ECGs), and outperforms ECG-FM and ECGFounder on shared external diagnostic classes.

Open-weight video-based deep neural network that predicts reduced right-ventricular systolic function (RVSF) directly from routine left and right coronary angiogram videos, enabling real-time RV-dysfunction screening in the catheterization lab when echocardiography is unavailable. Built on an X3D-M spatiotemporal video architecture (Kinetics-400 pretrained) that aggregates per-video probabilities into a study-level normal-vs-reduced RVSF classification, with Grad-CAM/Guided-Backpropagation explainability confirming attention to RV-specific coronary motion rather than left-ventricular signal. Trained on 8,053 angiographic studies from 6,923 Montreal Heart Institute patients (2017-2023), externally validated at UCSF, and prospectively deployed at MHI via the PACS-AI platform, where AI assistance improved reader accuracy from 72.1% to 77.6% for cardiologists and 43.5% to 64.0% for medical students.