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Interpretable LightGBM CHD Risk Model

Huzhou Central Hospital (Zhejiang Chinese Medical University / Huzhou University)

Structured EHR

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Text & EHR

Atherosclerotic cardiovascular disease (ASCVD) risk

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Prognosis & Aging

Binary classification

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Model weights not public. Contact creators for more information.

Interpretable coronary heart disease (CHD) risk prediction model based on the LightGBM gradient-boosting algorithm, combined with SHAP (SHapley Additive exPlanations) values to make individual risk predictions explainable to clinicians. Trained on the public BRFSS_2015 survey dataset and externally validated on the Framingham and Z-Alizadeh Sani datasets, the model reached 90.60% accuracy and 81.06% AUROC on BRFSS_2015, with SHAP analysis identifying age, smoking status, diabetes, hypertension, and high cholesterol as the most influential risk features. A companion CHD scoring system was built from the model to give clinicians a user-friendly risk-assessment tool.

memory Specifications

category

Architecture

Other

Gradient-boosted decision tree ensemble (LightGBM) over structured clinical/behavioral risk-factor features, with SHAP values used for post-hoc interpretability

calendar_month

Added to catalog

2026-08-14

description Publication

database Training & evaluation data

BRFSS 2015 (CHD risk subset)

train

public 253,680 subjects · USA · 2015

Framingham Heart Study (LightGBM CHD external validation subset)

validation

public 4,240 subjects · USA

Z-Alizadeh Sani Dataset

validation

public 303 subjects · Iran

science Capabilities & performance

Binary risk prediction of coronary heart disease from structured clinical/behavioral risk factors, with a derived CHD risk score

Binary classification Atherosclerotic cardiovascular disease (ASCVD) risk