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ProtoASNet

University of British Columbia

Echocardiography video

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Echocardiography

Valvular disease

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Structural Heart & Cardiomyopathy

Multi-class classification

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Classification

Hybrid

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Hybrid / Multi-branch

code View code

Model weights not public. Contact creators for more information.

Prototype-based neural network for interpretable, uncertainty-aware classification of aortic stenosis (AS) severity from B-mode echocardiography videos. Rather than a black-box prediction, ProtoASNet bases its output on similarity scores between the input video and a set of learned spatio-temporal prototypes (typically highlighting valve calcification and restricted leaflet motion), and uses an abstention loss to flag ambiguous/uncertain cases for expert review. Evaluated on a private clinical dataset and the public TMED-2 dataset, it achieved balanced accuracy of 80.0% (private) and 79.7% (TMED-2), improving to 82.4% when uncertain cases are excluded.

memory Specifications

category

Architecture

Hybrid

Prototype-based network: extracts spatio-temporal feature vectors from echo video, compares them against learned class prototypes via similarity scores, and aggregates these for both AS severity classification and aleatoric uncertainty estimation

calendar_month

Added to catalog

2026-08-14

description Publication

ProtoASNet: Comprehensive evaluation and enhanced performance with uncertainty estimation for aortic stenosis classification in echocardiography open_in_new

Vaseli H, Gu ARN, Ahmadi Amiri S, Tsang M, Fung A, Kondori N, Saadat A, Abolmaesumi P, Tsang T

Medical Image Analysis · 2025 · original paper

DOI: 10.1016/j.media.2025.103600

database Training & evaluation data

TMED-2 (Tufts Medical Echocardiogram Dataset)

test

USA

Public aortic-stenosis/view-classification benchmark; exact N not confirmed from paywalled sources, left blank rather than guessed

UBC/Vancouver General Hospital Private Echocardiography Dataset (ProtoASNet)

train

Canada

science Capabilities & performance

Aortic stenosis severity classification from echocardiography video with per-case aleatoric uncertainty estimate

Multi-class classification Valvular disease