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PLAX Severe-AS Ensemble

Yale School of Medicine (CarDS Lab)

Echocardiography video

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Echocardiography

Valvular disease

Filter catalog by Disease / Trait:
Structural Heart & Cardiomyopathy

Binary classification

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Classification

CNN (3D)

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Convolutional (CNN)

code View code

Model weights not public. Contact creators for more information.

Ensemble of 3D convolutional neural networks that detects severe aortic stenosis directly from single-view 2D parasternal long-axis (PLAX) transthoracic echocardiogram videos, without requiring Doppler imaging. Representations are first pretrained with patient-level contrastive self-supervised learning on PLAX clips, then fine-tuned for binary AS classification; the ensemble is externally validated across a temporally-distinct cohort and geographically-distinct cohorts in California and New England. No pretrained weights are released; only the training/evaluation pipeline is public.

memory Specifications

category

Architecture

CNN (3D)

Ensemble of 3D CNN video encoders (self-supervised contrastive pretraining compared against Kinetics-400-initialized and randomly-initialized baselines) fine-tuned for binary classification on PLAX echo clips

calendar_month

Added to catalog

2026-08-10

description Publication

database Training & evaluation data

Cedars-Sinai Medical Center Echocardiography Dataset

test

USA · 2011-2023

CSMC (Cedars-Sinai Medical Center) clinical echocardiography cohort: 877,983 individual sonographer measurements spanning 9 B-mode and 9 Doppler measurement types, drawn from 155,215 studies.

New England Hospitals Echocardiography Cohort (non-YNHH)

test

USA

External, geographically-distinct validation cohort of echocardiography studies from New England hospitals outside the Yale-New Haven Health network, used to test generalization of severe aortic-stenosis detection.

Yale-New Haven Hospital PLAX Echocardiography Cohort

testtrain

USA · 2016-2021

5,257 transthoracic echo studies (17,570 PLAX videos) from 2016-2020 used for training/internal validation of severe aortic-stenosis detection, plus a temporally-distinct 2021 test set of 2,040 studies from the same Yale-New Haven Health network.

science Capabilities & performance

Severe aortic stenosis presence, from single-view 2D PLAX echo without Doppler

Binary classification Valvular disease
0.978 (0.966–0.988) AUROC YNHH temporally-distinct 2021 test set · internal
0.952 (0.941–0.963) AUROC California external cohort · external
0.942 (0.909–0.966) AUROC New England external cohort · external