ECG-XPLAIM

National and Kapodistrian University of Athens / ETH Zurich (Pantelidis, Ruiperez-Campillo et al.)

12-lead ECG

Filter catalog by Modality:
ECG

Atrial fibrillation

Filter catalog by Disease / Trait:
Arrhythmia

Multi-class classification

Filter catalog by Task Type:
Classification

Multi-label classification

Filter catalog by Task Type:
Classification

CNN (1D)

Filter catalog by Architecture:
Convolutional (CNN)

TensorFlow

Filter catalog by Framework:
TensorFlow / Keras

CC BY 4.0

Filter catalog by License:
Open — Attribution

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Explainable Inception-style 1D CNN for multi-label arrhythmia detection from 12-lead ECGs, integrating Grad-CAM visualization to highlight the waveform segments driving each prediction. Trained on MIMIC-IV-ECG and externally validated on PTB-XL across atrial fibrillation, sinus tachycardia, conduction disturbances (RBBB/LBBB/LAFB), long QT, Wolff-Parkinson-White pattern, and paced-rhythm detection, with all metrics exceeding 90% internally and strong generalization on external validation.

memory Specifications

gavel License

CC BY 4.0

check_small Open source check_small Commercial use OK check_small Modifications allowed Attribution required No share-alike requirement

License for model weights only. Associated code may be licensed seperately, check code source for specific terms.

description Publication

ECG-XPLAIM: Deep learning tool for accurate and explainable arrhythmia detection from 12-lead electrocardiogram (ECG) signals open_in_new

Frontiers in Cardiovascular Medicine · 2025 · original paper

DOI: 10.3389/fcvm.2025.1659971

database Training & evaluation data

MIMIC-IV-ECG open_in_new

train

public 161,352 subjects · USA

800,035 12-lead ECG-report pairs from 161,352 subjects at Beth Israel Deaconess Medical Center.

PTB-XL open_in_new

test

public 18,885 subjects · Germany · 1989-1996

52% male / 48% female; age range 0-95 (median ~62). 21,837 10-second 12-lead ECG records.

science Capabilities & performance

Discrimination of atrial fibrillation vs. sinus tachycardia vs. non-arrhythmia from 12-lead ECG

Multi-class classification Atrial fibrillation

0.989 AUROC PTB-XL external validation (micro-averaged, AFib/sinus tachycardia/non-arrhythmia) · external

0.955 Sensitivity / recall PTB-XL external validation (micro-averaged sensitivity) · external

0.969 Specificity PTB-XL external validation (micro-averaged specificity) · external

Multi-label detection of conduction disturbances (RBBB/LBBB/LAFB), long QT, Wolff-Parkinson-White pattern, and paced rhythm