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MMCL-ECG-CMR

Technical University of Munich / Imperial College London

12-lead ECG

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ECG

General Purpose / Multi-task

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General / Foundation

Regression

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Regression

Hybrid

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Hybrid / Multi-branch

PyTorch

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PyTorch

MIT

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Permissive

Deep learning strategy for cost-effective, comprehensive cardiac screening from ECG alone, by transferring domain-specific structural information from cardiac magnetic resonance (CMR) imaging into ECG representations. Combines multimodal contrastive learning with masked data modelling during pretraining on paired ECG-CMR data, then uses only ECG at inference. On 40,044 UK Biobank subjects, the multimodal pretraining improved subject-specific CVD risk prediction by up to 12.19% and cardiac phenotype prediction by up to 27.59% versus ECG-only baselines, with learned ECG representations shown to incorporate information from CMR regions of interest.

memory Specifications

category

Architecture

Hybrid

Multimodal contrastive learning combined with masked data modelling (MAE-style) to transfer CMR-derived structural information into an ECG encoder during pretraining; only the ECG branch is used at inference

code

Framework

PyTorch

calendar_month

Added to catalog

2026-08-14

gavel License

MIT

check_small Open source check_small Commercial use OK check_small Modifications allowed Attribution required No share-alike requirement

License for model weights only. Associated code may be licensed seperately, check code source for specific terms.

description Publication

Unlocking the diagnostic potential of electrocardiograms through information transfer from cardiac magnetic resonance imaging open_in_new

Turgut O, Muller P, Hager P, Shit S, Starck S, Menten MJ, Martens E, Rueckert D

Medical Image Analysis · 2025 · original paper

DOI: 10.1016/j.media.2024.103375

database Training & evaluation data

UK Biobank Paired ECG-CMR Subset (MMCL-ECG-CMR)

train

public 40,044 subjects · United Kingdom

Subjects with paired 12-lead ECG and CMR from UK Biobank

science Capabilities & performance

ECG-derived representation used for CVD risk prediction and cardiac phenotype (CMR-derived measurement) prediction from ECG alone

Regression General Purpose / Multi-task