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CAC Scoring via Unsupervised Domain Adaptation (CCTA from NCCT)

Amsterdam UMC (Zhai et al.)

CT angiography

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Cardiac CT

Coronary artery calcium (CAC) scoring

Filter catalog by Disease / Trait:
Coronary & Ischemic Disease

Multi-class classification

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Classification

Hybrid

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Hybrid / Multi-branch

PyTorch

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PyTorch

code View code

Model weights not public. Contact creators for more information.

Coronary artery calcium (CAC) scoring model that transfers a CNN trained for calcium scoring on non-contrast CT (NCCT) to coronary CT angiography (CCTA), where iodinated contrast otherwise confounds calcium detection and large annotated CCTA training sets are scarce. The CAC-scoring CNN is split into a feature generator and a classifier; the feature generator is trained on the NCCT source domain and adapted to the CCTA target domain via adversarial learning combined with a maximum-mean-discrepancy loss, while the source-domain classifier is reused unchanged for the target domain. Builds directly on the authors' earlier non-contrast CT calcium-scoring network.

memory Specifications

category

Architecture

Hybrid

CAC-scoring CNN divided into a feature generator and a classifier; the feature generator is trained on NCCT (source domain) and adapted to CCTA (target domain) via adversarial learning and a maximum-mean-discrepancy loss, reusing the source-domain classifier unchanged

code

Framework

PyTorch

calendar_month

Added to catalog

2026-08-12

description Publication

Learning coronary artery calcium scoring in coronary CTA from non-contrast CT using unsupervised domain adaptation open_in_new

Zhiwei Zhai, Sanne G. M. van Velzen, Nikolas Lessmann, Nils Planken, Tim Leiner, Ivana Isgum

Frontiers in Cardiovascular Medicine · 2022 · original paper

DOI: 10.3389/fcvm.2022.981901

database Training & evaluation data

Amsterdam UMC Mixed Non-Contrast CT / Coronary CTA Cohort (Zhai domain adaptation)

testtrain

Netherlands

Paired non-contrast CT (source domain) and coronary CT angiography (target domain) scans used to train and adapt a coronary artery calcium scoring CNN via adversarial domain adaptation, building on the authors' earlier non-contrast CT calcium-scoring cohort.

science Capabilities & performance

Coronary artery calcium detection/scoring on coronary CT angiography (CCTA), using a feature generator adapted from non-contrast CT via unsupervised domain adaptation

Multi-class classification Coronary artery calcium (CAC) scoring