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Deep Vectorised Operators for Coronary Hemodynamics

University of Twente / Politecnico di Milano

CT angiography

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Cardiac CT

Fractional flow reserve (FFR) / coronary physiology

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Coronary & Ischemic Disease

Regression

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Regression

Hybrid

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Hybrid / Multi-branch

PyTorch

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PyTorch

code View code

Model weights not public. Contact creators for more information.

Machine-learning surrogate model for estimating pulsatile hemodynamic fields (velocity, pressure) in coronary arteries from a steady-state computational fluid dynamics (CFD) prior, avoiding the high computational cost of full pulsatile CFD. The model, a neural field conditioned on hemodynamic boundary conditions, is discretisation-independent and can be parametrised with message-passing or self-attention layers by relaxing point-wise action to permutation-equivariance. Evaluated on 74 stenotic coronary arteries from coronary CT angiography (CCTA) with patient-specific pulsatile CFD as ground truth, the model produced accurate, discretisation-independent estimates of pulsatile velocity and pressure fields.

memory Specifications

category

Architecture

Hybrid

Neural field / deep vectorised operator conditioned on steady-state hemodynamic boundary conditions, parametrised via message-passing or self-attention layers for discretisation-independent, permutation-equivariant estimation of pulsatile flow fields

code

Framework

PyTorch

calendar_month

Added to catalog

2026-08-14

description Publication

Deep vectorised operators for pulsatile hemodynamics estimation in coronary arteries from a steady-state prior open_in_new

Suk J, Nannini G, Rygiel P, Brune C, Pontone G, Redaelli A, Wolterink JM

Computer Methods and Programs in Biomedicine · 2025 · original paper

DOI: 10.1016/j.cmpb.2025.108958

database Training & evaluation data

CCTA Stenotic Coronary Artery Cohort (patient-specific CFD ground truth)

train

public 74 subjects

Stenotic coronary arteries extracted from CCTA with patient-specific pulsatile CFD ground truth; count is arteries, not necessarily unique patients

science Capabilities & performance

Pulsatile hemodynamic (velocity and pressure) fields in coronary arteries estimated from a steady-state CFD prior

Regression Fractional flow reserve (FFR) / coronary physiology