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CathAI

University of California, San Francisco (Avram, Tison et al.)

Coronary angiography

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Invasive Coronary & Intracoronary Imaging

Coronary artery segmentation / anatomy

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Coronary & Ischemic Disease

Coronary artery disease / stenosis

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Coronary & Ischemic Disease

Multi-class classification

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Classification

Detection / localization

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Segmentation & Detection

Binary classification

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Classification

Hybrid

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Hybrid / Multi-branch

description View paper

Training code and model weights not public. Contact creators for more information.

Fully automated pipeline for interpreting coronary angiograms that chains four purpose-built neural networks: (1) angiographic projection-angle identification, (2) left/right coronary artery detection, (3) arterial segment localization, and (4) stenosis-severity estimation. Trained on 13,843 angiographic studies (195,195 videos) from 11,972 adult patients at UCSF (2008-2019), with projection-angle and LCA/RCA-detection tasks each reaching precision/sensitivity/F1 at or above 90%. For predicting obstructive coronary artery disease (>=70% stenosis), CathAI reaches an AUC of 0.862 internally, 0.869 on external angiograms from the University of Ottawa Heart Institute, and 0.775 after retraining on quantitative-coronary-angiography labels from the Montreal Heart Institute core lab. No public code or model weights have been released.

memory Specifications

category

Architecture

Hybrid

Sequential pipeline of purpose-built CNNs: projection-angle classifier, LCA/RCA detector, arterial-segment localizer (with bounding boxes), and a stenosis-severity estimation network

calendar_month

Added to catalog

2026-08-10

description Publication

database Training & evaluation data

UCSF Coronary Angiography Cohort (CathAI)

testtrain

public 11,972 subjects · USA · 2008-2019

13,843 angiographic studies (195,195 total angiographic videos) from 11,972 adult patients; mean age 63.5 (SD 13.7) years.

University of Ottawa Heart Institute Angiography Cohort

test

Canada

Real-world coronary angiograms used as an external validation cohort for the CathAI stenosis-estimation pipeline.

science Capabilities & performance

Angiographic projection-angle identification and left/right coronary artery detection (pipeline stages 1-2)

Multi-class classification Coronary artery segmentation / anatomy

Localization of coronary artery stenosis within the angiogram

Detection / localization Coronary artery disease / stenosis

Binary classification of obstructive coronary artery disease (>=70% stenosis) from coronary angiogram segments

Binary classification Coronary artery disease / stenosis
0.862 (0.843–0.88) AUROC UCSF internal test set (obstructive CAD, >=70% stenosis) · internal
0.869 (0.83–0.907) AUROC University of Ottawa Heart Institute external validation · external
0.775 (0.594–0.955) AUROC Montreal Heart Institute QCA core-lab dataset (retrained) · external